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Reference: Mental Health and Non-Communicable Disease Management in Jamaica: A Quantitative Inquiry of Psychosocial Well-Being, Health Behaviours, and Patient Outcomes Non-communicable diseases (NCDs) such as diabetes, hypertension, and cardiovascular disorders represent a growing public health concern in Jamaica, with implications for both physical and mental health. Despite this burden, limited research has quantitatively examined the psychosocial well-being, health behaviours, and patient outcomes associated with NCD management in the Jamaican context. This study employs a cross-sectional quantitative design to assess the relationships among psychosocial well-being, health-promoting behaviours, and clinical outcomes among adults living with NCDs. Data were collected from a representative sample of patients attending primary healthcare facilities across Jamaica, using validated instruments measuring stress, anxiety, depression, adherence to treatment, dietary practices, and physical activity. Descriptive statistics, correlation analyses, and multiple regression models were conducted to evaluate the predictors of psychosocial well-being and patient outcomes. Findings are expected to identify critical psychosocial and behavioural determinants of effective NCD management, providing evidence-based insights for healthcare providers, policymakers, and public health practitioners. The current study contributes to the understanding of how mental health interacts with lifestyle behaviours and clinical management, highlighting the need for integrated care strategies that address both physiological and psychosocial dimensions. Ultimately, the research aims to inform interventions that enhance patient well-being, improve adherence, and reduce the long-term health burden of NCDs in Jamaica. Keywords: non-communicable diseases, mental health, psychosocial well-being, health behaviours, patient outcomes, Jamaica