Igor Lakhno
Biography
A clinical professor, and Head of the Department of Obstetrics and Gynecology No. 3 at Kharkiv National Medical University, Ukraine. He obtained his MD from the same University in 1994 specializing in Obstetrics and Gynaecology in 1997. Additionally, he gained his Ph.D. in 1999 from Kharkiv National Medical University and his DSC degree from the PL Shupik National Academy of Postgraduate Education in 2019. Dr. Lakhno is an author of about 250 printed works and there are 48 of them in Scopus or Web of Science databases. He is an Associate Editor at Cureus Medical Journal (part of Springer Nature), and a member of the Editorial Board at Reproductive Health of Woman (Ukraine), Emergency Medicine (Ukraine), and Technology Transfer: Innovative Solutions in Medicine (Estonia), and a consultant at the Kharkiv Municipal Perinatal Center. Dr. Lakhno participated as a speaker in several international conferences and congresses. His main scientific interests are obstetrics, women’s health, fetal medicine, and cardiovascular medicine.
Research Interest
Head of the Department of Obstetrics and Gynaecology No. 3 at Kharkiv National Medical University An author of about 250 printed works and there are 48 of them in Scopus or Web of Science databases
Abstract
On Agents of Women’s Health Programming
Menopause is an important stage in a woman's life. The age of menopause coincides with the onset of aging accompanied by the manifestation of many diseases. Hypoestrogeni?ity is a trigger for a significant number of comorbid to menopausal disorders. The theory of “fetal programming” (Barker’s hypothesis) of diseases contributes to a better understanding that fetal growth restriction leads to an increased level of cardiovascular diseases. There are no significant changes in the state of the vascular system before menopause. Hypoestrogenicity may be a trigger mechanism that causes atherogenic vasculopathy. It has been proven that disturbances in carbohydrate metabolism, chronic inflammation, and oxidative stress contribute to this. Aging is the sum of conditions preceding the disease and certain pathologies. Sometimes the development of complications precedes the clinical manifestation of the main disease. Progression from previous conditions to diseases occurs during early or late aging. Aging without diseases or healthy aging should be the norm.
It is known that the risk of mortality of women before the age of 55 from cardiovascular diseases in developed countries is increasing. There is no doubt that women with a history of preeclampsia should control their blood pressure and receive antihypertensive drugs if necessary. This women's category is managed after childbirth through joint consultation with a cardiologist, neurologist, and nephrologist. Chronic non-infectious inflammation, dyslipidemia, and obesity are known pathogenetic events in the total scenario of cardiovascular disease. All these factors may be associated with pathological pregnancy. Is there a certain risk of arterial hypertension after preterm birth or antenatal fetal death? The level of gestational comorbidities like diabetes mellitus and goiter disease is higher during the war in Ukraine. It is a serious challenge in the management of pregnant women. Gestational pathologies, a negative environmental influence, and wartime are the main factors contributing to cardiovascular disease. The enhanced atherogenicity was found in middle-aged internally displaced women in Ukraine. Therefore, programs preventing cardiovascular disease in women are important nowadays.
