Prof. Gayatri Hela Pamidipati is a scientist, innovator, and entrepreneur with over 20 years of international experience in green chemistry, nanotechnology, sustainable materials, and product development. She is the Founder and Managing Director of Reseda Life sciences and an Adjunct Research Professor at the University of Bamako, Mali. Her expertise includes sustainable chemistry, advanced materials, nanotechnology, and technology commercialization. She has collaborated with leading institutions across the UK, France, USA, Taiwan, and India and has contributed to patented innovations in sustainable technologies and advanced formulations.

Next-Generation Infection Prevention: Plant-Derived Antimicrobials, Advanced Delivery  Technologies and the One Health Approach

Abstract: The growing burden of infectious diseases and antimicrobial resistance has created an urgent  need for innovative, sustainable, and effective strategies for infection prevention and control.  Conventional antimicrobial and disinfectant approaches remain essential; however, concerns  related to resistance, environmental persistence, toxicity, and repeated chemical exposure  are driving interest in complementary technologies derived from renewable and biologically  active sources.

Plant-derived antimicrobials represent a promising class of bioactive compounds with broad potential across human health, veterinary care, environmental hygiene, and agricultural systems. Their practical application, however, can be limited by challenges such as poor water solubility, instability, volatility, variable bioavailability, and inconsistent delivery to target surfaces or biological systems. Advanced formulation and delivery technologies, including 
micellar and nano-enabled systems, can help overcome these limitations by improving solubility, stability, dispersion, controlled release, and functional performance.

This presentation will explore the scientific basis and emerging applications of plant-derived antimicrobial compounds integrated with advanced delivery platforms for next-generation infection prevention. Particular emphasis will be placed on their potential use in surface hygiene, antimicrobial coatings, institutional and healthcare environments, veterinary applications, and other high-risk settings where effective microbial control is critical.

The discussion will also examine these innovations through a One Health perspective, recognising the interconnected nature of human, animal, and environmental health. By combining biotechnology, green chemistry, formulation science, and preventive public health strategies, plant-based antimicrobial technologies may contribute to reducing microbial transmission, supporting responsible antimicrobial stewardship, and decreasing reliance on more environmentally persistent interventions.

A multidisciplinary approach integrating scientific validation, formulation innovation, safety assessment, regulatory compliance, and real-world performance will be essential for translating these technologies from laboratory research into scalable infection-prevention solutions. Such approaches may play an increasingly important role in strengthening preparedness for emerging infectious threats while supporting more sustainable public health systems. 

Suggested keywords: Plant-derived antimicrobials; infection prevention; antimicrobial resistance; micellar technology; drug delivery; One Health;biotechnology; sustainable disinfection; public health preparedness.