Dr. Vu Hai Phan is Associate Professor of Veterinary Medicine at the University of Agriculture and Forestry, Hue University, Vietnam. He earned his PhD in Veterinary Science from Utrecht University, the Netherlands in 2017, an MSc in Tropical Animal Science from James Cook University, Australia in 2004, and a Bachelor of Veterinary Medicine & Animal Husbandry from Hue University,  Vietnam in 1996. His research focuses on medicinal herbs, probiotics, poultry gut health, stress resilience, reproduction, and sustainable livestock production; he is the main author of ~20 papers indexed in Scopus, WoS, and SCIE. He has led national and university projects and developed patented/utility solutions for fermented Alliaceae products.

Evaluating a Water-Delivered Allium Phytobiotic-Probiotic Formulation for Heat-Stress Mitigation and AMR (Antimicrobial Resistance) Control in Broilers: A One Health Framework Heat–humidity stress impairs broiler productivity, intestinal integrity, and welfare, potentially increasing disease pressure and antimicrobial use. This study evaluates a water-delivered Allium phytobiotic-probiotic formulation within a One Health framework linking animal performance, antimicrobial resistance (AMR), farm-environment exposure, and food-chain contamination. Methodology: A randomized pen-based design was developed for 240 male Rilai broilers allocated to six treatments: thermoneutral control; heat-stressed control; heat stress + oxytetracycline; heat stress + red onion-chive phytobiotic; heat stress + Lactiplantibacillus plantarum 1582 and Bacillus subtilis BSn5; or heat stress + combined formulation. From days 15-42, heat-stressed birds were modeled under natural cyclic exposure to 34±1°C and 70±5% relative humidity for 8 h/day. The primary production endpoint was mortality-corrected feed conversion ratio (FCR), tested for noninferiority versus oxytetracycline, while the primary One Health endpoint was change in fecal intI1 abundance. Secondary outcomes included stress physiology, intestinal integrity, enteric microbiology, carcass contamination, multidrug-resistant Escherichia coli, and litter ammonia. Results: In the simulated dataset, heat stress worsened FCR from 1.55 to 1.66 and increased mortality from 2.5% to 10.0%. The combined formulation restored FCR to 1.55 and was noninferior to oxytetracycline. Compared with the antibiotic arm, it reduced fecal intI1 by 1.55 log10 copies/g, multidrug-resistant E. coli by 74%, carcass E. coli by 0.70 log10 CFU/mL, and litter ammonia by 29%, while improving stress, oxidative, intestinal-permeability, and villus-architecture indicators. Conclusion: These simulation-based findings support empirical evaluation of the combined Allium phytobiotic-probiotic strategy as a climate-resilient, antibiotic-sparing intervention with potential benefits across animal, environmental, and food-safety domains.