Bipul Kumar Sen is an aquaculture and fisheries researcher specializing in aquatic animal health, bacterial and viral diseases, molecular biology, immunology, vaccine development, host–pathogen interactions, and sustainable aquaculture. He holds a Master of Science in Aquaculture and Fisheries Management and a Bachelor of Science in Fisheries from Jashore University of Science and Technology (JUST), Bangladesh.

He has research experience with the Fish Molecular Laboratory at JUST, contributing to projects on shrimp and fish disease management, molecular surveillance, vaccine development, water quality monitoring, and sustainable aquaculture practices. His research includes work on Vibrio parahaemolyticus, acute hepatopancreatic necrosis disease (AHPND), viral hemorrhagic septicemia (VHS), shrimp immunity, and aquatic pathogen detection.

Bipul has contributed to several peer-reviewed publications in areas including aquatic disease prevention, environmental DNA monitoring, molecular identification, antimicrobial resistance, shrimp immunity, and disease management. He has also received the Dean’s Award, Best Poster Presentation Award, and National Science and Technology (NST) Fellowship for his academic and research achievements.

Molecular Surveillance and Immunomodulation for the Prevention and Control of Viral Hemorrhagic Septicemia (VHS) in Labeo rohita Aquaculture:                                                         

Viral Hemorrhagic Septicemia (VHS) poses a significant threat to freshwater aquaculture, particularly in Labeo rohita. This study aimed to integrate molecular surveillance with dietary immunomodulation to develop an effective prevention and control strategy against VHS. Field samples collected from aquaculture farms in Jashore, Bangladesh, were analyzed using multi-gene PCR targeting the N, G, and L genes of VHSV. A high detection rate (70%) confirmed active viral circulation, with the kidney identified as the primary target organ (85% positivity). A controlled 8-week feeding trial was conducted using functional diets enriched with β-glucan, vitamin C, and turmeric powder as immunostimulants. Fish fed supplemented diets exhibited significantly improved growth performance, including higher final weight, enhanced specific growth rate, and reduced feed conversion ratio compared to control. Hematological and innate immune responses were markedly elevated, with increased WBC count, lysozyme activity, respiratory burst, complement activity, and phagocytic capacity. Gene expression analysis revealed significant upregulation of key immune markers (IL-1β, IFN-γ, Mx, IRF-1, IRF-7), indicating enhanced antiviral preparedness. Following VHSV challenge, treated groups demonstrated substantially reduced mortality (31.03-43.33%) compared to control (76.92%), with Relative Percent Survival reaching up to 59.65% at 28 days post infection. Viral load was significantly lower in treated fish, confirming improved viral resistance. Overall, this study demonstrates that combining molecular surveillance with dietary immunomodulation provides a robust and sustainable strategy for controlling VHS in L. rohita aquaculture.